The Greatest Little Lines in Movie History

[mrsskinner]

"anything you didn't feed the food to Mrs. Skinner?"-Food of the Gods

Also from that film:

"Jobs for female bacteriologists are just not that easy to find, Jack."

also
"The only sin is your G-d stupidity"

[Allhallowsday]

MARLON BRANDO in THE GODFATHER:
"I'll make him an offer he can't refuse." 

BORIS KARLOFF in THE BRIDE OF FRANKENSTEIN:
"Hate living.  Love dead."

GENE WILDER in YOUNG FRANKENSTEIN (after TERI GARR exclaims "Oh Doctor, you haven't touched your food...") 
"There.  Now I've touched it.  Happy?" 

[LilCerberus]

"Oh, yeah- A man, in a cylinder, unscrewin' it from another world? You're a lunatic!" - The Potsman from Timbo Hines' WOTW

[crackers]

"C'mon let's do some crime" Debbie from Repo Man.

[molokai cargo]

One of my favourites (2 actually)

- Don't cry son, tears will cause thy wheels to rust

Roller blade

- A date without sex is a day wasted

Birdemic

[alandhopewell]

     JOHN CONNOR- "The police are outside!"

     SARAH CONNOR- "How many?"

     JOHN CONNOR- "All of them!"

     From TERMINATOR 2: JUDGEMENT DAY

[indianasmith]

"I HATE robot spiders!" - from THE LOST EMPIRE

[tracy]

"You ruined my new jacket...kill him a lot!"

Amilyn,aka Paul Reubens from "Buffy the Vampire Slayer" movie

[BoyScoutKevin]

"When Harry Met Sally'

Harry (Billy Crystal) and Sally (Meg Ryan) are in a restaurant in New York City discussing female orgasms, and to prove that a woman can fake a convincing orgasm, Sally starts faking one. Throwing her head and body back and saying: "Yes! Yes! Yes!"

But another woman in the restaurant thinking that Sally is enjoying what she is eating,  says to a waiter: "I'll have what she's having."

Only five words, but a memorable line I'll never forget. For it is not what you say, but how you say it.

[Leah]

"OHHHH MY GOD!!!!!!!!!!!!!"
-Troll 2

"I'm tired of the muthaf**king snakes on this muthaf**king plane!"
-Samuel L. Jackson Snakes on a Plane

[ChaosTheory]

"Now this just p!sses me off to no end." - BIG TROUBLE IN LITTLE CHINA

"Go away. 'Batin'."
and
"So?? Shut up! You broke my house!" -- IDIOCRACY  (pretty much everything Frito says in that movie is golden  )

[tracy]

"You've got two empty halves of coconuts and you're banging them together!"

"So?"

From Monty Python and the Holy Grail....just the way Graham Chapman says "So?" simply cracks me up.

[alandhopewell]

     "You broke the ship! You BROKE the bloody SHIP!"

     -Alan Rickman (Dr. Lazarus) in GALAXY QUEST

[Zapranoth]

For pure dramatic punch, I'd go with "It won't make any difference."

(Newt, from Aliens)

For a line that is just incidental-seeming but genius in its way, I'd go with Otto's final line in this exchange from Repo Man:

Leila: What about our relationship?
Otto: What?
Leila: Our relationship!
Otto: f**k that!

[BoyScoutKevin]

It is not only how you say it, but how you write it.

In "Lair of the White Worm," in the scene with the lady (Amanda Donohoe) and the underaged scout (Chris Pitt), there must be some type of record for double entendres in one scene, as seemingly, every other line is a double entendre or one about every 23 seconds.

Here are some examples from the lady, and when two people are speaking, the boy speaks first, except for the first one listed.

"How do you rate the music?"--"I'm not really into head banging."--"Are you into any kind of banging?"

"Don't worry. You will leave me well satisfied."

"That's very kind."--"Kind nothing. If you don't get out of your wet things, you'll catch your death."

"Down you go."

"Yes, I'm home."

"I'm hungry."--"Me, too. Dinner won't be long."

"So, it's a nice bath for you and then dinner."

"And after that."--"Ah! The experience of a lifetime."

"I wouldn't think of letting you go--now."

"There. That's just a sample. Bathtime."

"I'm not finished with you--yet."

"Stand up. I won't bite you."

"My, you are a fine growing boy."

"Save your breath."

"You are a vegetable, metaphorically speaking. But, the god is not a vegetarian."

"Actually, I'm doing you a favor."

And the perfect answer to the inevitable question from the lord to the lady. "Do you have any children?"--"Only when there are no men around."

Of course, depending upon one's sexual orientation, one may substitute "Only when there are no women around" for "Only when there are no men around.