Here's the main cast of the series:

From left to right:
Peter Rucker (played by Stephen T. Kay) - As Gus' lab assistant, Peter must help Gus find a way to get his parade of villains off the streets and back into the game. A seen-it-all New Yorker, even Peter is amazed at the quality and quantity of his colleague's neuroses, as evidenced by his video game creations.
Dr. Gus Lloyd (played by James Calvert) - A brilliant young scientist, Gus' breakthrough discovery of anti-matter may earn him a place in history -- not as the recipient of a Nobel Prize, but as the guy who inadvertently unleashed pure evil onto the world. As a way of dealing with a painful divorce, Gus created a video game in which the villains look like people he has known and have exaggerated versions of their quirks and peccadilloes... but are far more deadly (in Gus' words, "It was a lot cheaper than therapy"). When an accident in his lab brings these bad folks to "life" and forces Gus into the unlikely role of hero, he must enlist the aide of his ex-wife and his lab assistant to maintain order in the world.
Lauren Ashborne (played by Cynthia Gibb) - Gus' beautiful ex-wife had almost made it to the altar again when his lab accident changed her life. Unaware that Gus had even created a video game, Lauren was extremely surprised to find herself cast as "the girl" -- love interest and loyal sidekick to Gus' "Cold Steel Kid." Once it sinks in that without her help, Gus is powerless against his evil creations, Lauren grudgingly submits. With one problem remaining: how do you explain to your fiancé that you missed meeting him for vital wedding preparations because you had to stop a maniacal football player -- armed with miniature football bombs -- from dropping a nuclear warhead on the L.A. Coliseum?
And finally, the villain of the piece --
Sebastian Jackal (played by Christopher Lloyd) - Think Satan with a sense of whimsy. Jackal, dressed in immaculate white, is the quintessential bad guy. Always appreciative of a glass of fine champagne, nothing makes him thirstier than some well-executed death and destruction. His turn-ons include the ultimate control of life on earth, and he volunteers his time helping apprentice villains hone their craft. In the weeks to come, the person in Gus' life upon whom Jackal is based will reappear.
Any clues as to where I can find this show would be greatly appreciated!