My experience:
.45 acp : Breaks them, , as expected
.357 Magnum: Same as .45
7MM Remmington Magnum: Breaks them better, at longer range.
.338 Winchester Magnum: Pulverizes them, at long range.
.444 Marlin: Pulverizes them even better, but not at such a long range.
12 Gauge 000 Buck: Effective, but not as dramatic
12 Gauge Slug X 2: Quite dramatic destruction.
Or you could just leave the drive on the busy highway between Pretoria and Johannesburg. I give that drive 5 minutes, no more.